S-adenosylmethionine (also known as SAMe) is a molecule found in every cell in the body. SAMe is of particular importance in hepatocytes, where it has the ability to positively influence whole-body metabolism. It contributes to the formation of Glutathione, the most important defense mechanism against oxidative stress, as it helps to detoxify harmful molecules, making them soluble and thus facilitating their excretion. Glutathione protects hepatocytes from cell deterioration and death (apoptosis). When the liver is damaged, the enzymatic activity of SAMe synthetase decreases. This causes methionine to increase and SAMe levels to decrease. Due to this reduction, less glutathione is synthesized, causing liver failure that can affect the entire body's metabolism.

Silybin is the most abundant and active component of silymarin, an extract from the fruit of milk thistle ( Silybum marianum ). Silybin neutralizes free radicals, thus protecting liver cells from oxidative damage. Silybin inhibits the adhesion of toxins as well as the production of leukotrienes, which are involved in the inflammatory response. As for phosphatidylcholine, it is the main precursor/metabolite of choline and the main constituent of lipoproteins in the bloodstream and cell membranes. It is also the main component of bile and plays a key role in transforming mitochondrial energy and eliminating waste from cellular metabolism.

Recommended use:
Nutritional aid for dogs and cats to help maintain liver function.

Each Prolivet small dog & cat tablet contains:
- Oxomet®: Product derived from the fermentation of S. cerevisiae rich in Sa: 420.42 mg
- sodium pyrophosphate
- yeast, lupine protein flour, mono and diglycerides of fatty acids,   sunflower oil , magnesium stearate
- Vitamin E (50% alpha-tocopherol, 3 to 700): 52.5 mg
- flavoring: Siliphos®(silybum marianum, phosphatidylcholine(lecti): 84.50 mg

Each Prolivet medium dog tablet contains:
- Oxomet®: Product derived from the fermentation of S. cerevisiae rich in S-cerevisae: 504 mg
- Sodium pyrophosphate
- Yeast, lupine protein flour, mono and diglycerides of fatty acids, sunflower oil , magnesium stearate.
- Vitamin E (50% alpha-tocopherol, 3 to 700): 52.5 mg.
- Flavoring: Siliphos® (silybum marianum, phosphatidylcholine (lecti): 84.50 mg

Each Prolivet Large Dog tablet contains:
- Oxomet®: Product derived from the fermentation of S. cerevisiae rich in S-cerevisae: 1,008 mg
- Sodium pyrophosphate
- Yeast, lupine protein flour, mono and diglycerides of fatty acids, sunflower oil , magnesium stearate.
- Vitamin E (50% alpha-tocopherol, 3 to 700): 105 mg.
- Flavoring: Siliphos®(silybum marianum, phosphatidylcholine(lecti): 168 mg

Prolivet Small Breeds & Cats:
- 1cp (0 - 5 kg)
- 2cp (6 - 10kg)

Prolivet medium breeds:
- 1cp (7 - 15kg)

Prolivet large breeds:
- 1cp (16 - 30 kg)
- 2cp (31 - 50kg)
- 3cp (+ 50kg)

It is recommended to administer the tablets while the animal is hungry, at least one hour before food intake, to ensure optimal absorption. The animal must have constant access to water. Administer Prolivet ® orally for a minimum of 30 days.

The period of administration may be extended at the discretion of the veterinarian.